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The Prevalence of Deep Venous Thrombosis in Patients with Suspected Paradoxical Embolism Ann Int Med 119:461-465, Stollberger,C.,et al, 1993 See this aricle in Pubmed Article Abstract Venous thrombosis was clinically suspected in 6 patients and documented in 24 of the 42 patients with patent foramen ovale who underwent venographic study(57%;95%CI,41%to 72%).Venous thrombosis was confined to calf or popliteal veins in 15 cases.Fifteen of 17 patients who had venographic evaluation within 7 days of the index event had thrombosis compared with 9 of 25 patients who had later evaluations(P=0.001).More patients with venous thrombosis than without venous thrombosis had a history of previous thromboembolism(13 of 24 compared with 1 of 8,respectively;P=0.001).When a patent foramen ovale is detected in a patient with embolism,occult leg vein thrombosis is frequently present.

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