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Transcranial Doppler Detection of Circulating Cerebral Emboli, A Review
Stroke 24:1246-1250, Markus,H., 1993
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Article Abstract
Solid emboli such as thrombi and platelet aggregates result in less intense signals than air emboli.Their detection,using Doppler ultrasound, has recently been described in patients with prosthetic heart valves, atrial fibrillation,and carotid artery disease.It may also help in the detection and localization of embolic sources in patients with stroke. Studies in in vitro and in vivo models demonstrate that this technique provides information on the size and type of emboli.Larger emboli produce signals of greater intensity and duration.Practical patient monitoring will require automatic emboli detectors incorporated into the Doppler machine;such programs are being developed.Detection of solid emboli using Doppler techniques offers an exciting new diagnostic tool.It has been demonstrated that the technique can detect solid emboli.The prognostic significance of such emboli remains to be determined.It is hoped that the technique will allow detection of patients at high risk of embolic stroke in whom appropriate prophylactic treatment can then be instituted.
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advances in neurology
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