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Intracerebral Hemorrhage After Fibrinolytic Therapy for Acute Myocardial Infarction
C. R. , Stroke 24:554-557, 5233., Wijdicks,E.F.M.&Jack,Jr, 1993
See this aricle in Pubmed

Article Abstract
For most patients,outcome was fatal within hours of the ictus.Compared tomography scans showed superficially large lobar hematomas in six patients.One patient had a putaminal hemorrhage,and one had a vermis hemorrhage.Multiple sitels of intracerebral hemorrhage were noted in three patients.Fluid levels inside the hematoma suggesting continuing hemorrhage into multiple compartments were common.Radiologically,fluid levels in hematomas,multiple hematomas,and blood in multiple compartments served to differentiate fibrinolysis-induced hemorrhage from hemorrhage of other causes.Severe amyloid angiopathy was found in one patient who was operated on.Hemorrhages in multiple compartments and the presence of fluid levels inside the hematoma suggest fibrinolysis-associated cerebral hematomas. Severe amyloid angiopathy may be a crucial factor in this clinical entity. Outcome is poor,and a high proportion of patients have rapid progression to brain death.Therefore,emergency neurosurgical evacuation will probably be unsuccessful.
 
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amyloid angiopathy,cerebral
CAT scan
CAT scan,abnormal
CAT scan,fluid-blood level
fibrinolytic agents
fibrinolytic agents,complications
iatrogenic neurologic disorders
intracerebral hemorrhage
intracerebral hemorrhage,lobar
intracerebral hemorrhage,multiple
intraventricular hemorrhage
myocardial infarction
myocardial infarction,acute
prognosis
streptokinase
subarachnoid hemorrhage
tissue plasminogen activator,intravenous

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