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Amygdala Atrophy in Alzheimer's Disease, An In Vivo MRI Study Arch Neurol 50:941-945, Cuenod,C.A.,et al, 1993 See this aricle in Pubmed Article Abstract The values obtained by the two observers correlated highly(r=.90),and interrater variability was 13%.The Alzheimer's disease group showed significant(33%;P<.0001)atrophy of the amygdala when compared with the control group.The other structures showed less variation.Significant amygdala atrophy can be detected in vivo in patients with early Alzheimer' s disease by means of standard magnetic resonance imaging.This technique may be useful in the early diagnosis of Alzheimer's disease.

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