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A postpartum patient,initially presenting with headaches,subsequently manifested rapid neurological deterioration after ingesting isometheptene, a sympathomimetic drug.She was not on any ergot derivative but presented similar clinical and radiological manifestations.She experienced increased headache severity,visual disturbance,and seizures associated with multiple segmental cerebral vasoconstriction on angiography and increased T2- weighted signal in the occipital areas on magnetic resonance imaging.This case is additional evidence that sympathomimetic actions of some drugs, such as ergot derivatives and isometheptene,may lead to postpartum cerebral angiopathy.Documentation of medication used by postpartum women suffering similar complications is needed to verify these findings. |
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adverse drug reaction angiography,cerebral cerebrovascular accident cerebrovascular accident,postpartum headache MRI MRI,abnormal occipital lobe,infarction,bilateral postpartum postpartum cerebral angiopathy pregnancy,neurologic complications in sympathomimetic drugs vasospasm,cerebral
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