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Asymptomatic Carotid Lesions and Silent Cerebral Infarction Stroke 25:566-570, Hougaku,H.,et al, 1994 See this aricle in Pubmed Article Abstract The incidence of silent infarcts was 42%in all subjects and significantly increased with advancing age(P<.05).Most lesions were smaller than 1 cm in diameter and were usually localized in the subcortical white matter or the basal ganglia.The percentage of subjects with infarcts increased significantly as the plaque score increased(P<.05)or when subjects had high-grade stenosis(P<.05)or ulcerated lesions(P<.01).These relationships were also noted in each decade of age.A higher incidence of larger lesions (>1 cm)was found in the brain hemisphere ipsilateral to the carotid lesion,particularly in subjects with high-grade stenosis or ulcerated lesions(P<.01).multivariate analysis indicated significant correlations with silent infarcts for age,hypertension,and plaque score.Both the severity and characteristics of asymptomatic carotid lesions estimated by B-mode ultrasonography were closely related to the appearance of silent infarcts.These results demonstrated that noninvasive assessment of carotid lesions can be useful in predicting the existence of silent cerebral infarction even in patients free from neurological deficits.

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(click to filter results - removes previous filter) carotid artery atherosclerosis carotid artery disease carotid artery disease,asymptomatic carotid artery plaque carotid artery stenosis cerebral infarction cerebrovascular accident cerebrovascular accident,silent ultrasonography ultrasonography,carotid artery

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