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Demyelinating lesions,such as those in multiple sclerosis,may resemble primary or metastatic brain tumors on CT or MRI,and even be mistaken for neoplasms on biopsy.We encountered five such patients in whom an incorrect diagnosis of CNS neoplasm was made on the basis of radiologic appearance (five)and biopsy(four).All five received radiation therapy,and three chemotherapy.Review of the pathologic findings indicated that the original lesions were not neoplastic but demyelinative.The four patients who received radiation in full tumoricidal doses had expectedly poor clinical outcome,suggesting that radiation is especially injurious to patients with demyelinating disease. |
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brain biopsy CAT scan CAT scan,abnormal demyelinating disease gadolinium headache misdiagnosis MRI MRI,abnormal MRI,contrast enhanced MRI,demyelinating disease multiple sclerosis multiple sclerosis,misdiagnosis neoplasm,metastatic to CNS neoplasm,primary intracerebral neoplasm,primary of CNS radiation therapy,CNS treatment and complications with
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