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We report the first case of nonconvulsive status epilepticus as a complication of chemotherapy with the nitrogen mustard derivative ifosfamide.Our patient developed encephalopathy,upper extremity myoclonus, and a periodic,triphasic electroencephalogic pattern that resolved acutely with intravenous diazepam treatment.Since significant morbidity and mortality is associated with unrecognized status epilepticus, electroencephalogic monitoring and a trial of diazepam is indicated in the encephalopathic patients with rhythmic electroencephalogic patterns while receiving treatment with ifosfamide. |
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