Neurology Specific Literature Search   
 
[home][thesaurus]
    
Click Here to return To Results

 

Value of Magnetic Resonance Imaging-Based Measurements of Hippocampal Formations in Patients with Partial Epilepsy
Arch Neurol 51:130-138, Adam,C.,et al, 1994
See this aricle in Pubmed

Article Abstract
Hippocampal atrophy was present in 70%of patients with cryptogenic temporal lobe epilepsy(TLE)(n=40),44%of patients with symptomatic TLE(n= 9),29%of patients with extratemporal epilepsy(n=14),and 6%of unclassified patients(n=16).In the cryptogenic TLE category,HA was marked and usually concordant(93%)with electroencephalographic lateralization.Hippocampal atrophy was often mild in the extratemporal epilepsy category.With the use of a wider confidence interval(+/-3.1 SD instead of+/-2.2 SD),HA specificity for TLE increased to 93%,HA specificity for lateralizing cryptogenic TLE reached 96%,and HA sensitivity for cryptogenic TLE stood almost unchanged(68%).We found a link between early convulsions and HA occurrence.Hippocampal atrophy is a marker for TLE.Dual pathologic findings are detected in 44%of symptomatic TLE cases.Mild HA is rarely associated with extratemporal epilepsy.Magnetic resonance imaging-based hippocampal volumetric analysis is a useful method to localize the origin of partial complex seizures.
 
Related Tags
(click to filter results - removes previous filter)

hippocampus
mesial temporal sclerosis
MRI
MRI,abnormal
MRI,volumetry
seizure
seizure,focal
seizure,focus
seizure,intractable
seizure,psychomotor-temporal lobe

Click Here to return To Results