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Twenty-three of the 86 children(27 percent)had a recurrence of tumor.Four recurrences(17 percent)were detected on scanning only,and 19(83 percent) were associated with symptoms arising a median of four months after the previous scan.The median and range of survival after a recurrence of the tumor were 5 months and<1 to 38 months,respectively,for a symptomatic recurrence and 20 months and 10 to 32 months,respectively,for a radiographic recurrence(P=0.03).No patient survived after a recurrence.The longer survival of patients with recurrent tumors detected by scanning most likely reflects the small number of patients and lead-time and length biases associated with screening.Among children with medulloblastoma, surveillance scanning is of little clinical value.Scanning detected a minority of recurrences,and no patient who had a recurrence survived. |
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children
medulloblastoma
MRI
MRI,abnormal
neoplasm,posterior fossa
neoplasm,primary of CNS
neoplasm,primary of CNS-children
neoplasm,primary of CNS-recurrent
prognosis
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