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Clinical Assessment of Extrapyramidal Signs in Nursing Home Patients Given Antipsychotic Medication
Arch Int Med 154:1113-1117, Avorn,J.,et al, 1994
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Article Abstract
Clinical evidence of extrapyramidal dysfunction is three to six times more common in institutionalized elderly patients given antipsychotic medication than in comparable patients not using such drugs.Its risk is substantially increased even in patients given low-potency chlorpromazine- type drugs,as well as those taking haloperidol.The effect is not explained by age or mental status and is not seen with other psychoactive medications.The expected frequency of parkinsonian symptoms can help to inform the balancing risks vs therapeutic effect when the use of all drugs in this class is considered.
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chlorpromazine
haloperidol
movement disorder
movement disorder,drug induced
movement disorder,extrapyramidal
neuroleptic
nursing home
old age,neurology of
Parkinson disease
Parkinson disease,drug induced
Parkinsonism syndrome
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