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Three patients with antibiotic induced meningitis,one following penicillin with seven episodes,are reported on-the first well documented description of penicillin induced meningitis.In this patient episodes of headache and nuchal rigidity appeared with and without CSF pleocytosis.Two patients had a total of five episodes of antibiotic induced meningitis after trimethoprim-sulphamethoxazole(co-trimoxazole)administration.The features common to all three patients were myalgia,confusion and low CSF glucose. CSF analysis was not a reliable method to differentiate antibiotic induced meningitis from partially treated bacterial meningitis. |
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