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Excessive Muscular Fatigue in the Postpoliomyelitis Syndrome
Neurol 44:642-646, Sharma,K.R.,et al, 1994
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Article Abstract
To investigate anterior tibial muscle fatigability and metabolism in postpoliomyelitis syndrome patients and controls,we performed measurements of force and relaxation time,as well as 31 P magnetic resonance spectroscopy,during intermittent,low-intensity,isometric,voluntary exercise.Taken together,the findings of increased fatigability,delayed recovery,and prolonged half-relaxation time,without differences in metabolites,suggest that the fatigue in postpoliomyelitis syndrome may be due to impaired activation beyond the muscle membrane.
 
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