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Neuroanatomy of Fragile X Syndrome:The Temporal Lobe
Neurol 44:1317-1324, Reiss,A.L.,et al, 1994
See this aricle in Pubmed
Article Abstract
Subjects with the fragile X mutation showed an age-related increase in volume of the hippocampus and an age-related de4crease in volume of the superior temporal gyrus.Along with the findings of previous imaging studies of fragile X subjects,the results of the present investigation are consistent with studies showing a nonrandom distribution of expression of the FMR-1 gene in the developing brain,with increased expression in the cerebellum,hippocampus,and specific cortical regions.The results also suggest involvement of temporal lobe regions in the behavioral and cognitive abnormalities associated with fragile X syndrome.
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anatomy of
fragile-X syndrome
hippocampus
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MRI,abnormal
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temporal lobe,anatomy and physiology
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