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Choreiform Movements Associated with the Use of Valproate
Arch Neurol 51:702-704, Lancman,M.E.,et al, 1994
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Article Abstract
Valproic acid-associated chorea occurred in patients with severe epilepsy and brain damage.It may occur after several years of valproic acid use and may be more likely to develop if valproic acid is taken together with phenytoid.Because valproic acid-associated chorea seemed to be dose- related,avoiding excessive fluctuations of serum levels by the use of divalproex sodium sprinkles may be an effective solution in these cases.
 
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adverse drug reaction
anticonvulsants
anticonvulsants,untoward effects of
chorea
drug induced neurologic disorders
movement disorder
movement disorder,drug induced
sodium valproate
sodium valproate,toxicity

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