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We report two cases of Marchiafava-Bignami disease studied by CT and MRI. Both patients displayed persistent confusion and a disconnection syndrome but had a favourable outcome.In both cases,CT with intravenous contrast medium revealed enhancement of the corpus callosum in the early stage.MRI showed gadolinium uptake in both the genu and splenium of the corpus callosum in one case,8 days after the onset.Three weeks after admission, cystic lesions appeared in the corpus callosum on MRI T1-weighted sagittal images in both cases.Contrast medium uptake may be useful in the diagnosis of Marchiafava-Bignami disease. |
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alcohol alcohol,neurologic complications with alcoholism CAT scan CAT scan,abnormal CAT scan,contrast enhanced confusion corpus callosum corpus callosum,cyst of corpus callosum,lesion of demyelinating disease disconnection syndrome gadolinium genu of corpus callosum Marchiafava-Bignami disease MRI MRI,abnormal MRI,contrast enhanced MRI,demyelinating disease splenium of corpus callosum
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