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Topical Lidocaine Gel Relieves Postherapetic Neuralgia
Ann Neurol 37:246-253, Rowbotham,M.C.,et al, 1995
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Article Abstract
The 23 subjects with torso or limb PHN reported significantly lower pain intensity with local drug application at 8 hours and both pain relief and reduced pain intensity at 24 hours.Remote lidocaine application to mirror- image skin was no different from placebo.No systemic adverse effects were reported and blood levels did not exceed 0.6 ug/ml.Topical application of 5%lidocaine gel relieves PHN pain by a direct drug action on painful skin.
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lidocaine
lidocaine,topical
pain
pain,management of chronic
post herpetic neuralgia
treatment of neurologic disorder
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