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Larger infarcts,more embolic infarcts,and fewer lacunar infarcts were observed in the poor-outcome group.Vascular risk factors,radiological findings not related to the index stroke,time to admission,and treatment were similar in the two outcome groups.Variables with statistically significant differences between outcome groups included the following:age> 65 years,female sex,admission Mathew score<75,worsening at clinical presentation,infarct volume>6cm3,complicating infections,fasting glucose> 110 mg,nonfasting glucose>130 mg,and elevated ESR.With stepwise logistic regression analysis,Mathew score on admission,infarct volume,mode of clinical presentation,and ESR remained in the predictive model of stroke outcome,with a sensitivity and specificity of 89.91%and 85.71%, respectively.After removing the computed tomographic information from the model the same variables remained,with a sensitivity and specificity of 83.05%and 94.29%,respectively.Infarct size and clinical severity on admission are the stronger predictors of short-term functional outcome. Mode of clinical presentation,clinical evolution during the first day of stroke,and ESR are also independent predictors of short-term stroke outcome.These findings might be indicative of an inadequate collateral profile and/or a more pronounced prothrombotic state. |
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