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Safety and Efficacy of Percutaneous Transluminal Angioplasty for Intracranial Atherosclerotic Stenosis
Stroke 26:1200-1204, Clark,W.M.,et al, 1995
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Article Abstract
The average preangioplasty stenosis(North American Symptomatic Carotid Endarterectomy Trial criteria)was 72+/-8%(mean+/-SD),with a significant improvement seen after angioplasty;the best angiographic stenosis(after healing of intimal injury,if any)was 43+/-24%(P<.001).Overall PCTA was successful in 82%of the vessels.There were two strokes during angioplasty for a 30-day morbidity rate of 9.1%per vessel and 11.7%per case.The other 15 patients were clinically evaluated at 3 and 6 months;all cases were without further events.Restenosis was evaluated in 8 patients(12 vessels) with an angiogram at 6 months showing further improvement compared with initial post-PCTA stenosis(51+/-10%versus 37+/-21%[P=.05]).PCT may be a beneficial therapy in selected cases of symptomatic intracranial atherosclerotic stenosis.Further study using a randomized trial is needed.
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basilar artery
basilar artery stenosis
carotid artery
carotid artery atherosclerosis
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carotid artery stenosis,intracranial
endovascular therapy
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middle cerebral artery,stenosis of
neuroradiology,interventional
transluminal angioplasty,carotid artery
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treatment of neurologic disorder
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