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We describe two patients with fulminant acute disseminated encepahlomyelitis(ADEM)treated with plasmapheresis after they failed to improve on steroids.Both patients improved concomitant with the plasma exchange.These are the first reported cases of fulminant ADEM with extensive white matter abnormalities on imaging studies treated with a regime of plasmapheresis and steroids.Plasmapharesis may be beneficial in this disorder. |
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