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We investigated the relationships between prevalent coronary heart disease (CHD),clinically manifest atherosclerotic disease(ASD),and major established risk factors for atherosclerosis and intima-media thickness (IMT)in the common carotid arteries(CCA)and internal carotid arteries(ICA) separately and in combination in older adults.We wished to determine whether a noninvasive measurement can serve as an indicator of clinically manifest atherosclerotic disease and to determine which of the two variables,CCA IMT or ICA IMT,is a better correlate.Whereas CCA IMT is associated with major risk factors for atherosclerosis and existing CHD and ASD in older adults,this association is not as strong as that for ICA IMT.The combination of these measures relates more strongly to existing CHD and ASD and cerebrovascular disease risk factors than either taken alone. |
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