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Of 55 ocular motor signs,33 involved limitation of eye movements or abnormal eye position at rest;abnormal spontaneous eye movements occurred 12 times;ptosis was seen in eight patients and psychogenic signs in two. Sixteen patients(48%)had brainstem infarcts;11 had other known causes, including three with meningitis,two with hysteria,and one each with ocular myositis,pseudotumor cerebri,both ocular myositis and pseudotumor cerebri, Guillain-Barre syndrome,hyperosmolality,and hypoxic encephalopathy.In four patients with isolated sixth nerve palsies and two with isolated ptosis, the cause remained unknown.Ocular motor signs in SLE are uncommon and often transitory.When present,they help to ascertain the location,and often the cause,of neurologic involvement. |
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