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In 100 consecutive patients with Guillain-Barre syndrome,we assessed liver function on admission and at fixed intervals after either intravenous immunoglobulin(IgIV)or plasma-exchange(PE)treatment.On admission,38%shoed a plasma alanine aminotransferase elevation,gama glutamyl transferase elevation,or both of more than 1.5 times the upper limit of normal.We concluded that may patients with Guillain-Barre syndrome had mild liver function disturbances without obvious cause.In addition,IgIV treatment was associated with mild transient liver function disturbances through an unknown mechanism. |
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