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Campylobacter Jejuni Infection and Guillain-Barre Syndrome NEJM 333:1374-1379, 14151995., Rees,J.H.,et al, 1995 See this aricle in Pubmed Article Abstract There was evidence of recent C.jejuni infection in 26 percent of the patients with Guillain-Barre or Miller Fisher syndrome,as compared with 2 percent of household controls and 1 percent of age-matched hospital controls(P<0.001).Of the 27 patients with C.jejuni infection,19(70 percent)reported having had a diarrhea illness within 12 weeks before the onset of the neurologic illness.No specific serotypes were associated with Guillain-Barre syndrome.C.jejuni infection was slightly more common in men (P=0.14)and was more likely to be associated with a pure motor syndrome and a slower recovery(P=0.03).The patients with preceding C.Jejuni infection were more likely to have acute axonal neuropathy or axonal degeneration in association with acute inflammatory demyelinating polyradiculoneoropathy,and they had greater disability after one year(P=0. 02).C.jejnui infection was significantly associated with a poor outcome even after correction for other factors associated with a poor prognosis. Infection with C.jejuni often precedes the Guillain-Barre syndrome and is associated with axonal degeneration,slow recover,and severe residual disability.

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(click to filter results - removes previous filter) bacterial infection campylobacter infection diarrhea disability,neurological ELISA Fisher's syndrome gastroenteritis gram negative rod Guillain Barre syndrome Guillain Barre syndrome,axonal form Guillain Barre syndrome,etiology of Guillain Barre syndrome,prognosis of prognosis serologic testing stool culture

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