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Decreased SPECT[123I]B-CIT Striatal Uptake Correlates with Symptom Severity in Parkinson's Disease Ann Neurol 38:589-598, Seibyl,J.P.,et al, 1995 See this aricle in Pubmed Article Abstract Previous studies have utilized single-photon emission computed tomography (SPECT)to demonstrated decreased{123I}B-CIT striatal uptake in idiopathic Parkinsons disease(PD)patients.These data demonstrate marked differences in{123I}B-CI SPECT measures in healthy controls and PD patients.The significant correlation of SPECT measures with motor severity suggests{ 123i}B-CIT may be a useful marker of disease severity in PD.

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(click to filter results - removes previous filter) disability rating scale,neurological disability,neurological Parkinson disease single photon emission computed tomography

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