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The incidence of recurrent brain infarction was 11.9 per 100 person-years in patients with an aortic wall thickness of>4 mm,as compared with 3.5 per 100 person-years in patients with a wall thickness of 1 to 3.9 mm and 2.8 per 100 person-years in patients with a wall thickness of<1 mm(P<0.001). the overall incidence of vascular events was 26.0,9.1,and 5.9 per 100 person-years of follow-up in the respective groups(P<0.001).After adjust for the presence of carotid stenosis,atrial fibrillation,peripheral arterial disease,and other risk factors,aortic plaques>4 mm thick (including the thickness of the aortic wall)were found to be independent predictors of recurrent brain infarction(relative risk 3.8;95 percent confidence interval,1.8 to 7.8;P=0.0012)and of all vascular events (relative risk,3.5;95 percent confidence interval,2.1 to 5.0;P<0.001). Atherosclerotic plaques>4 mm thick in the aortic arch are significant predictors of recurrent brain infarction and other vascular events. |
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