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Five patients with stroke or head trauma developed a cerebellar syndrome 3 weeks to 2 years after the initial insult.The syndrome,characterized by intention tremor,ataxic dysarthria,nystagmus,dysmetria,dysdiadochokinesis, and gait ataxia,was progressive in at least one patient.In four patients, lesions were present on neuroimaging,in the thalamus or brainstem (especially in the mid brain).A delayed-onset cerebellar syndrome may follow head trauma or stroke.The syndrome is sometimes progressive and often disabling.The delayed onset implies that the syndrome is not caused by the initial lesion itself but may be caused by the development of postsynaptic supersensitivity or secondary reorganization of involved pathways. |
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