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Dementia and Adult-Onset Unprovoked Seizures
Neurol 46:727-730, Hesdorffer,D.C.,et al, 1996
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Article Abstract
We tested the hypothesis that dementia increases the risk of unprovoked seizure among adults.Partial-and generalized-onset seizures were considered together and separately.Additionally,we explored whether the increased risk was restricted to Alzheimer's disease(AD),as previously shown.Both a diagnosis of AD and a diagnosis of other dementia were associated with at least a six-fold increased risk of unprovoked seizure when controlling for age,sex,and length of medical follow-up in Rochester. There was no difference in risk when comparing generalized-onset seizures with partial-onset seizures.Conclusions:In the absence of other prior neurologic insult,both AD and other dementias increase the risk of generalized-and partial-onset unprovoked seizures.
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Alzheimer's disease
dementia
risk factors
seizure
seizure,elderly
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seizure,risk factors for
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