Neurology Specific Literature Search   
 
[home][thesaurus]
    
Click Here to return To Results

 

Tuberculous Meningitis Among Adults with and without HIV Infection
Arch Int med 156:1710-1716, Yechoor,V.K.,et al, 1996
See this aricle in Pubmed

Article Abstract
Among 31 adult patients identified as having definite or probable tuberculous meningitis,a majority(n=20[65%])were infected with HIV. Cumulative rates of occurrence per 100,000 persons over the 12 years of the study were estimated at 1.72 for those without HIV infection and 400 for those with HIV infection.The most common symptoms at presentation were fever(83%[24/29])and abnormal mental status(71%[20/28]).One or more abnormalities were present in the cerebrospinal fluid of 97%(30/31)of subjects and 74%(23/31)had cerebrospinal fluid cultures positive for Mycobacterium tuberculosis.Neuroimaging of 28 patients revealed 1 or more abnormalities in 82%(n=23).Among 30 patients with available outcome data at 9 months,43%(n=13)had died,40%(n=12)had survived without sequelae,and 17%(n=5)had survived with morbidity.HIV infection had no discernible effect on findings.Tuberculous meningitis remains relatively common among indigent urban nonwhite populations.While HIV infection has contributed to the increased incidence of tuberculous meningitis,it has not significantly altered the presenting clinical,laboratory,or radiographic findings or the response to therapy of this disease.Parameters associated in a multivariate regression analysis with mortality at 9 months were black race and the absence of corticosteroid use.
 
Related Tags
(click to filter results - removes previous filter)

acquired immunodeficiency syndrome
blacks
CAT scan
CAT scan,abnormal
chest x-ray,abnormal
epidemiology of neurology
human immunodeficiency virus type 1
hydrocephalus
meningeal thickening
meningitis
meningitis,adults
meningitis,clinical features of
meningitis,CSF findings in
meningitis,neurologic aspects and complications of
meningitis,TB
mortality
opportunistic infection
opportunistic infection,CNS
prognosis
steroid therapy,CNS treatment and complications with

Click Here to return To Results