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Triple Dose of Gadolinium-DPTA and Delayed MRI in Patients with Benign Multiple Sclerosis JNNP 60:526-530, Filippi,M.,et al, 1996 See this aricle in Pubmed Article Abstract Nine enhancing lesions were found in seven patients(35%)using the standard dose of Gd-DTPA.The numbers of enhancing lesions increased to 13(P=0.03) and the number of patients with such lesions to eight(40%)on the delayed standard dose scans.On the early triple dose scans,we found 19 enhancing lesions in 10 patients(50%).The number of enhancing lesions was significantly higher(P=0.01)than that obtained with the early standard dose.The number of enhancing lesions was 18 and the number of"active" patients 11(55%)on the delayed triple dose scans.The enhancing areas increased progressively from the early standard dose scans to the delayed triple dose scans.The contrast ratios of the lesions detected in the early standard dose scans was lower that those of lesions present in the early (P=0.01)and delayed(P=0.04)triple dose scans.More enhancing lesions were detected in patients with benign multiple sclerosis with both delay of MRI and the use of a triple dose of Gd-DPTA suggesting that the amount of inflammation in the lesions of such patients is mild and heterogeneous.

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(click to filter results - removes previous filter) gadolinium MRI MRI,abnormal MRI,contrast enhanced MRI,contrast enhanced,delayed MRI,contrast enhanced,high dose multiple sclerosis multiple sclerosis,benign form of

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