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Early Hemorrhage Growth in Patients with Intracerebral Hemorrhage
Stroke 28:1-5, Brott,T.,et al, 1997
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Article Abstract
Substantial growth in the volume of parenchymal hemorrhage occurred in 26% of the 103 study patients between the baseline and 1-hour CT scans.An additional 12%of patients had substantial growth between the 1-and 20-hour CT scans.Hemorrhage growth between the baseline and 1-hour CT scans was significantly associated with clinical deterioration,as measured by the change between the baseline and 1-hour Glasgow Coma Scale and National Institutes of Health Stroke Scale scores.No baseline clinical or CT prediction of hemorrhage growth was identified.Substantial early hemorrhage growth in patients with intracerebral hemorrhage is common and is associated with neurological deterioration.Randomized treatment trials are needed to determine whether this early natural history of ongoing bleeding and frequent neurological deterioration can be improved.
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