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We examined the bone marrow in our first evaluation of 161 patients with MND seen at Columbia-Presbyterian Medical Center during 1991-1994.Four of 161 patients(2.5%)had lymphoproliferative disease in the marrow;only 1 of these had a monoclonal paraprotein.Routine bone marrow examination of patients with MND increases in the diagnostic yield of lymphoproliferative diseases.The frequency of these bone marrow abnormalities in comparison with a group of age-matched control subjects should be studied further. |
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