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Cost-Effectiveness of Screening for Carotid Stenosis in Asymptomatic Persons
Ann Int med 126:337-346, Lee,T.T.,et al, 1997
See this aricle in Pubmed
Article Abstract
When the conditions an results of ACAS were modeled and it was assumed that the survival advantage produced by endarterectomy would last for 30 years,the lifetime marginal cost effectiveness of screening relative to no screening was$120,000 per quality-adjusted life-year.Sensitivity analysis showed that marginal cost effectiveness decreased to$50,000 or less per quality-adjusted life-year only under implausible conditions(for example, is a free screening instrument with perfect test characteristics was used or an asymptomatic population with a 40%prevalence of carotid stenosis was found).Surgery offers a real but modest absolute reduction in the rate of strokes at a substantial cost.A program to identify candidates for endarterectomy by screening asymptomatic populations for carotid stenosis costs more per quality-adjusted life-year than is usually considered acceptable.
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carotid artery disease
carotid artery disease,asymptomatic
carotid artery disease,noninvasive evaluation of
carotid artery stenosis
cerebrovascular accident,prevention of
cost effectiveness
duplex ultrasound
prevention of neurologic disorders
ultrasonography
ultrasonography,carotid artery
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