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P3 Latency Change in Aging and Parkinson Disease
Arch Neurol 54:296-302, Tachibana,H.,et al, 1997
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Article Abstract
The P3 component of the event-related potentials was elicited during a visual semantic discrimination task.The relation of the P3 latency and the reaction time(RT)to age within each group was evaluated using correlation and regression analysis.The relationship among the P3 latency,the RT,and age was also assessed by dividing both groups into younger(age<60 years) and older(age>/=60 years)subgroups.The P3 latency and the RT of patients with PD were significantly longer than those of the control subjects(P<.01 and P<.02,respectively).The results provide evidence that patients with PD experience excessive cognitive slowing with advancing age.
 
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old age,neurology of
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