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Systematic Review of Evidence on Thrombolytic Therapy for Acute Ischaemic Stroke
Lancet 350:607-614, Wardlaw,J.M.,et al, 1997
See this aricle in Pubmed

Article Abstract
Thrombolysis requires further testing in large randomized trials because the risks seem substantial,and the benefit uncertain.The time window for effective treatment remains unclear.There is no objective evidence to suggest that tPA is safer than streptokinase;the apparent hazards and benefits may be similar when differences in trial design and baseline variables are accounted for.
 
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adverse drug reaction
cerebrovascular accident
cerebrovascular accident,acute management of
cerebrovascular accident,thrombolytic agents in treatment
fibrinolytic agents
fibrinolytic agents,complications
practice guidelines
review article
streptokinase
tissue plasminogen activator,intravenous
treatment of neurologic disorder

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