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Embolic Brain Infarction in Nonrheumatic Atrial Fibrillation Neurol 48:1593-1597, Yamanouchi,H.,et al, 1997 See this aricle in Pubmed Article Abstract Although CT studies have addressed symptomatic and asymptomatic cerebral infarctions in nonrheumatic atrial fibrillation(NRAF),pathologic verification of the results is lacking.The purpose of this study was to asses the frequency,location,and extent of symptomatic and asymptomatic brain infarction in autopsy specimens from elderly patients with NRAF.We examined autopsy specimens from 136 consecutive NRAF patients 70 years of age or older who received no anticoagulant therapy during their lifetime and compared them with 231 age-matched control subjects with similar health histories except for the absence of NRAF.In this autopsy series of individuals over 70 years of age,symptomatic brain infarction was 2.5 times more common in NRAF patients than in NRAF-free control subjects;two- thirds of the infarction in the NRAF cases were judged to be cardioembolic in origin.Most asymptomatic cerebral infarction in the NRAF patients were located in the cortices.

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(click to filter results - removes previous filter) asymptomatic atrial fibrillation atrial fibrillation,nonvalvular cerebral embolism cerebral embolism,cardiac origin cerebral infarction cerebrovascular accident cerebrovascular accident,silent mortality neuropathology old age,neurology of prognosis

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