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Painful Proximal Diabetic Neuropathy:Inflammatory Nerve Lesions and Spontaneous Favorable Outcome
Ann Neurol 41:762-770, Said,G.,et al, 1997
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Article Abstract
Proximal diabetic neuropathy is a disabling neuropathy that occurs predominantly in noninsulin dependent diabetic patients over the age of 50.Inflammatory lesions have been found in nerve biopsy specimens of diabetic patients with severe proximal neuropathy or with other patterns of multifocal neuropathy.Some of these patients respond dramatically to treatment with corticosteroids or with other immunomodulators.In this article we report findings in 4 additional patients with painful proximal diabetic neuropathy and different patterns of inflammatory nerve lesions whose condition improved spontaneously shortly after performance of a nerve biopsy without additional treatment.
 
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diabetes mellitus
diabetes mellitus,neurologic manifestations of
diabetic amyotrophy
leg weakness,unilateral
muscle weakness,proximal
nerve biopsy
neuropathy,diabetic
neuropathy,painful
neuropathy,short-fiber
pain
pain,leg
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treatment of neurologic disorder

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