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Posteroventral Medial Pallidotomy in Levodopa-Unresponsive Parkinsonism
Arch Neurol 54:1026-1029, Krauss,J.K.,et al, 1997
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Article Abstract
We treated the patient with microelectrode-guided unilateral posteroventral medial pallidotomy and followed up with magnetic resonance imaging and prospective clinical evaluation.Pallidotomy resulted in marked improvement of right-sided parkinsonian symptoms and functional disability at 4.5 months after surgery.Microelectrode recording during pallidotomy revealed discharge patterns that were similar to those seen in patients with Parkinson disease.Post-operative magnetic resonance imaging confirmed the location of the lesion in the posteroventral medial pallidum. Posteroventral pallidotomy usually has limited benefit in patients with degenerative atypical parkinsonism who do not respond to levodopa therapy. Nevertheless,pallidotomy can be an effective treatment for other levodopa- unresponsive parkinsonian disorders.
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head injury
pallidotomy
Parkinson disease
Parkinson disease,L-dopa nonresponsive
Parkinson disease,surgical treatment of
Parkinson disease,treatment of
stereotaxic surgery
treatment of neurologic disorder
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