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During mean followup of 8.5 months for the hemorrhage group and 11.9 months for the nonhemorrhage group,hemorrhages occurred in 18(13%)of the former patients and in three(2%)of the latter(p=0.0002).The annual risk of hemorrhage was 17.8%and 2.2%respectively.In the multivariate regression model,the adjusted hazard ratio for hemorrhage at initial presentation was 13.9(95%CI 2.6-73.8;p=0.0002).Deep venous drainage(hazard ratio 4.1[1.2- 14.9],p=0.029)and male sex(9.2[2.1-41.3],p=0.004)were also significantly associated with subsequent hemorrhage,but no significant association was found for age or AVM size.The annual rate of spontaneous hemorrhage was 32.6%for men and 10.4%for women in the hemorrhage group compared with 3.3% for mean and 1.3%for women in the nonhemorrhage group.Among patients with hemorrhage at initial presentation,the risk of hemorrhage fell from 32.9% in year 1 to 11.3%in subsequent years(34.2%to 31.0%in men;31.1%to 5.5%in women).In AVM,patients initially presenting with hemorrhage have a higher risk of subsequent bleeding than those presenting with other symptoms.The risk is higher in men than in women. |
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CAT scan,abnormal
cerebrovascular accident,sex distribution
intracerebral hemorrhage
intracerebral hemorrhage,recurrent
malformation,vascular
malformation,vascular,cerebral
malformation,vascular,treatment of
MRI,abnormal
prognosis
risk factors
treatment of neurologic disorder
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