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Pallidal Stimulation for Parkinson's Disease, Two Targets
Neurol 49:1564-1569, Bejjani,B.,et al, 1997
See this aricle in Pubmed
Article Abstract
Our results indicate that stimulation had a striking different effect on parkinsonism and dyskinesia when applied at two different loci of the GP and that stimulation applied in the posteroventral GP produced opposite effects on rigidity and on akinesia.We conclude that parkinsonian signs and LID are a reflection of at least two different anatomofunctional systems within the GP and that this functional organization of the GP needs to be considered when determining the optimal target for surgical treatment of PD.
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globus pallidus,stimulation
pallidotomy
Parkinson disease
Parkinson disease,surgical treatment of
Parkinson disease,treatment of
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