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Comparison of T2-Weighted & Fluid-Attenuated Inversion-Recovery Fast Spin-Echo MR Seq in Intracerebral AIDS-Assoc Dis
AJNR 18:1601-1609, 16111997., Thurnher,M.W.,et al, 1997
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Article Abstract
FLAIR was found to be superior to T2-weighted fast spin-echo in detection of small lesions and lesions located in cortical/subcortical regions and deep white matter.The two techniques were equal in delineation of lesions larger than 2 cm and for lesions located in the basal ganglia and posterior fossa.In 24 patients,more lesions were detected with the FLAIR fast spin-echo technique.Lesion/cerebrospinal fluid contrast ratios and contrast-to-noise ratios were significantly higher for the FLAIR fast spin-echo sequences than for the T2-weighted fast spin-echo sequence.FLAIR allows early detection of small lesions in subcortical and cortical locations,especially in HIV encephalitis.Because of its improved lesion detection rate and greater overall lesion conspicuity,we believe FLAIR is useful in the evaluation of subtle changes in the brains of AIDS patients with central nervous system disease,and could even replace the T2-weighted fast spin-echo technique.
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acquired immunodeficiency syndrome
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human immunodeficiency virus type 1
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MRI,FLAIR
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