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Chronic Inflammatory Demyelinating Polyradiculoneuropathy in Children
Muscle & Nerve 20:1569-1575997., Simmons,Z.,et al, 1997
See this aricle in Pubmed
Article Abstract
We previously reviewed the presentation,initial clinical course and electrodiagnostic features of children with chronic inflammatory demyelinating polyradiculoneuropathy(CIDP).We now report the long term followup of 12 children with idiopathic CIDP and compare these to 62 adults with idiopathic CIDP.Children often had more rapidly fluctuating courses than adults.The recovery of children from each episode of deterioration was usually excellent and better on average than in adults. Ventilatory support was never required for children with slowly evolving illness;only 2 children with a precipitous onset clinically resembling Guillain-Barre syndrome required ventilatory support.Prednisone,plasma exchange and intravenous immunoglobulin usually were effective in children.Multiple courses of IVIg could be given with continued efficacy. Treatment often could be discontinued in children with relapsing courses. The prognosis for children was excellent.Adults demonstrated a good,but more variable outcome.
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children
gammaglobulin therapy,intravenous
polyneuropathy,chronic inflammatory demyelinating
polyneuropathy,chronic inflammatory demyelinating,childhood
prognosis
treatment of neurologic disorder
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