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In high risk patients with atrial fibrillation,subsequent rates of thromboembolism are correlated with dense spontaneous echocardiographic contrast,thrombus of the atrial appendage and aortic plaque.Adjusted-dose warfarin reduces the rate of stroke among patients with dense contrast and complex plaque.In patients with atrial fibrillation,the pathogenesis of stroke is multifactorial,and warfarin seems effective for the diverse mechanisms. |
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