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We included 61 studies that involved 2460 patients(57%female;mean age 50 years)and at least 2568 unruptured aneurysms(27%>25 mm,30%located in the posterior circulation).Mortality was 2.6%(95%confidence interval[CI],2.0% to 3.3%).Permanent morbidity occurred in 10.9%(95%,CI,9.6%to 12.2%)of patients.Postoperative mortality was significantly lower in more recent years for nongiant aneurysms and aneurysms with an anterior location;the last 2 characteristics were also associated with a significantly lower morbidity.In studies published between 1966 and 1996 on clipping of unruptured aneurysms,mortality was 2.6%and morbidity was 10.9%.In calculating the pros and cons of preventive surgery,these proportions should be taken into account. |
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aneurysm aneurysm,asymptomatic aneurysm,giant cerebral aneurysm,intracranial aneurysm,intracranial,natural history aneurysm,intracranial,treatment of aneurysm,unruptured controversies in neurology mortality treatment of neurologic disorder
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