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Early Intravenous Thrombolysis with Recombinant Tissue-Type Plasminogen Activator in Vertebrobasilar Ischemic Stroke Arch Neurol 55:466-469, 4501998., Grond,M.,et al, 1998 See this aricle in Pubmed Article Abstract On admission,7 patients exhibited moderate to severe brainstem symptoms without impairment of consciousness and 5 patients has impairment of consciousness,of whom 2 were comatose.Of 12 patients,10 had a favorable outcome after 3 months defined as full independence(Barthel index score of 100)or return to premorbid condition.One patient has a poor outcome with complete dependence due to reocclusions after primarily successful thrombolysis,and 1 patient died of severe brainstem infarction and additional space occupying parietal hemorrhage.Favorable outcome could be achieved in the majority of 12 consecutive patients with moderate to severe vertebrobasilar ischemic stroke treated with intravenous recombinant tissue-type plasminogen activator 3 hours after symptom onset.

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(click to filter results - removes previous filter) brainstem,ischemia cerebrovascular accident cerebrovascular accident,acute management of cerebrovascular accident,thrombolytic agents in treatment fibrinolytic agents fibrinolytic agents,complications tissue plasminogen activator,intravenous treatment of neurologic disorder vertebral-basilar insufficiency

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