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Longitudinal Study of CSF Levels of Tau, A beta 1-40, and A beta 1-42 (43) in Alzheimer's Disease Ann Neurol 44:17-26, 61998., Kanai,M.,et al, 1998 See this aricle in Pubmed Article Abstract These findings suggest that CSF tau may increase with the clinical progression of dementia and that the alteration of the CSF level of AB-42 (43)and the ratio of AB1-40 to AB1-42(43)may start at early stages in AD. The assays of CSF tau,AB1-40 and AB1-42(43)provided efficient diagnostic sensitivity(71%)and specificity(83%)by using the production of tau levels and the ratio of AB1-40 to AB1-42(43)and an improvement in sensitivity(to 91%)was obtained in the longitudinal evaluation.

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(click to filter results - removes previous filter) Alzheimer's disease Alzheimer's disease,diagnosis of amyloid amyloid beta protein cerebrospinal fluid cerebrospinal fluid,abnormal dementia neurologic disease,diagnoses of tau protein

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