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The Risk of Parkinson's Disease with Exposure to Pesticides, Farming, Well Water, and Rural Living
Neurol 50:1346-1350, Gorell,J.M.,et al, 1998
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Article Abstract
We assessed exposure to pesticides,farming,well water use and rural living as risk factors for Parkinson's disease(PD)in a population-based case- control study consisting of men and women>/=50 years of age who had primary medial care at Henry Ford Health System in metropolitan Detroit. Enrolled PD patients(n=144)and control subjects(n=464)were frequency- matched for age,race,and sex.The association of occupational exposure to herbicides or insecticides with PD remained after adjustment for farming. The association of arming with PD was maintained after adjustment for occupational herbicide exposure and was of borderline significance after adjustment for occupational insecticide exposure.These results suggest that PD is associated with occupational exposure to herbicides and insecticides and to farming and that the risk of farming cannot be accounted for by pesticide exposure alone.
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