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Ischemic Core and Penumbra in Human Stroke Stroke 30:93-99, Kaufmann,A.M.,et al, 1999 See this aricle in Pubmed Article Abstract Our study in acute human stroke involving MCA occlusion indicates that a severely ischemic core observation between 1 to 6 hours after stroke onset, corresponds to the cerebral tissue destined to infarction. The ischemic penumbra with flow values between 7 and 20 cm3 surrounding the ischemic core is very narrow. Therefore, strategies to improve the outcome of many patients with acute MCA occlusion must either include interventions to reverse the ischemic process within a few minutes of onset or increase the cerebral tolerance of ischemia and thereby prolong the potential therapeutic window.

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(click to filter results - removes previous filter) CAT scan,emission CAT scan,emission,abnormal CAT scan,xenon-enhanced cerebral blood flow cerebral infarction cerebral ischemia cerebrovascular accident ischemic penumbra middle cerebral artery,occlusion of neuroprotective agents

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