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The Efficacy of Ginkgo Biloba on Cognitive Function in Alzheimer Disease Arch Neurol 55:1409-1415, Oken,B.S.,et al,, 1998 See this aricle in Pubmed Article Abstract Based on a quantitative analysis of the literature, there is a small but significant effect of 3- to 6- month treatment with 120 to 240 mg of G biloba extract on objective measures of cognitive function in AD. The drug has not had significant adverse effects in formal clinical trials but there are 2 case reports of bleeding complications. In AD, there are limited and inconsistent data that preclude determining if there are effects on noncognitive behavioral and functional measures as well as on clinician's global rating scales. Further research in the area will need to determine if there are functional improvements and to determine the best dosage. Additional research will be needed to define which ingredients in the ginkgo extract are producing its effect in individuals with AD.

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