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Fatal Enterovirus 71 Encephalomyelitis
J Pediatrics 133:796-798, Lum,L.C.S.,et al, 1998
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Article Abstract
During an outbreak of hand-foot-mouth disease caused by enterovirus 71 (EV-71) in 1997, 4 children presented with sudden cardiopulmonary collapse and minimal neurologic features. All children received cardiopulmonary resuscitation but died within a few hours of admission. Postmortem studies showed infection by EV-71 with extensive damage to the medulla and pons. We postulate an etiologic link between EV-71 and brainstem encephalomyelitis as the cause of pulmonary edema and death.
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brainstem,lesion of
encephalitis,brainstem
encephalomyelitis
enterovirus
enterovirus infection of CNS
hand-foot-mouth disease
mortality
pulmonary edema
viral infection
viral infection,CNS
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